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doi: 10.1586/17446651.2014.960845 246 GoriniFSabatinoL

187,218 Although the onset of PCOS frequently occurs near the onset of puberty, diagnosing PCOS in girls and younger women is complicated by the fact that high levels of androgens and menstrual irregularities are common during puberty

BRAF plays a vital role in the mitogen-activated protein kinases/extracellular signal-regulated kinases (MAPK/ERK) signaling pathway, which influences cell growth and proliferation (226)

Furthermore, the use of animal models is limited for ethical reasons by increasingly stringent regulations